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Electroconvulsive therapy (ECT) is the most effective treatment for severe depressive disorder, and yet the mechanisms of its therapeutic effects remain largely unknown. A novel computational model is presented in this study to simulate and investigate direct cortical excitation caused by bitemporal electroconvulsive therapy (BT ECT), using a finite element model (FEM) of the human head. The skull...
The simulation of electrical activity in the heart, such as normal and abnormal ventricular rhythms and ischemia, utilize computational methods that rely on an underlying geometric model, or polygonal mesh of cardiac tissues and boundaries. Because of the complex shape of many biological structures, it is often difficult to create meshes that conform to the boundaries between distinct regions. The...
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