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Acute lymphoblastic leukemia (ALL) is the most common hematological neoplasia of childhood and is characterized by uncontrolled growth of leukemic cells in bone marrow, lymphoid organs etc. The nonspecific nature of the signs and symptoms of ALL often leads to wrong diagnosis. Diagnostic confusion is also posed due to imitation of similar signs by other disorders. Careful microscopic examination of...
Acute lymphoblastic leukemia (ALL) is an serious hematological neoplasia of childhood which is characterized by abnormal growth and development of immature white blood cells (lymphoblasts). ALL makes around 80% of childhood leukemia and it mostly occur in the age group of 3-7. The nonspecific nature of the signs and symptoms of ALL often leads to wrong diagnosis. Diagnostic confusion is also posed...
A multimodal method, which uses different kinds of imaging methods, was applied to extract cell membranes in microscopic images of hematoxylin and eosin-stained hepatic histological sections. Cell membrane extraction in hepatic histological images is difficult because the color difference between the cell membrane and the cytoplasm is small in bright-field images. Three kinds of imaging methods, bright-field,...
A mainstay in cancer diagnostics is the classification or grading of cell nuclei based on their appearance. While the analysis of cytological samples has been automated successfully for a long time, the complexity of histological tissue samples has prevented a reliable classification with machine vision techniques. We approach this complex problem in multiple stages, analyzing first image quality,...
This study investigates the potential of applying the radial basis function (RBF) neural network architecture for the classification of biological microscopic images displaying lung tissue sections with idiopathic pulmonary fibrosis. For the development of the RBF classifiers, the fuzzy means clustering algorithm is utilized. This method is based on a fuzzy partition of the input space and requires...
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