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Zahlreiche Befunde deuten darauf hin, dass Defekte in den apoptotischen Signalkaskaden wesentlich zur Therapieresistenz von malignen Tumoren beitragen. Der mangelhafte Ablauf des apoptotischen Selbstmordprogramms ist nicht nur eine wichtige Ursache für die Entstehung von Krebs, sondern erhöht auch die Resistenz von malignen Tumoren gegenüber Chemotherapie und Bestrahlung. Daher ist es von großer Bedeutung,...
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