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Background and Objectives With four transfusion related transmissions of variant Creutzfeldt–Jakob Disease (vCJD), three of which developed clinical disease and the other died of other causes but was positive for markers of infection, there is an increased urgency to identify and implement a test for blood donor screening. With limited amounts of blood samples from vCJD cases available test evaluation...
Background and Objectives
Effective recruitment and retention of male donors are vital for the ongoing provision of blood products. Compared with females, male donors are less likely to be medically deferred or experience vasovagal reactions and are typically preferred for plasmapheresis donation in voluntary non‐remunerated settings. However, females outnumber males among donors aged under 40 years...
Background and Objectives
Although screening of donated blood for syphilis is almost universally applied, its cost‐effectiveness is questioned because of the low prevalence of transfusion‐transmitted syphilis and a widespread belief that the syphilis‐causing bacterium Treponema pallidum is very vulnerable to cold storage. Since the latter claim is not yet supported by a systematic review, we investigated...
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