A small pediatric deceased donor (SPD) weight cutoff whether to transplant as en bloc (EB) or single pediatric (SP) kidney is uncertain. Using UNOS/OPTN data (2000–2019), 27 875 SPDs were divided by (i) EB (11.4%) or SP (88.6%) and (ii) donor weight [≤10 (5.4%), >10–15 (8.3%), >15–18 (3.7%), >18–20 (2.9%), and >20 kg (79.7%)]. SP >20 kg and adult deceased donors (grouped by Kidney Donor Profile Index, KDPI, <30, 30–85, and >85) were used as references. The primary outcome was 10‐year graft failure. In SP <10 kg, the hazard ratio (HR) for overall graft failure was 1.64 (1.38–2.20) compared with EB <10 kg, and 1.45 (1.18–1.80) compared with SP >20 kg. In SP >10–15 kg, HR was 1.31 (1.12–1.54) compared with EB >10–15 kg, and 1.04 (0.91–1.18) compared with SP >20 kg. In SP >15 kg, the risk was the same as SP >20 kg. Ten‐year overall graft survival of SP 12 kg was comparable to SP >20 kg (62% vs. 57%). Ten‐year death censored graft failure of SP >10–15 kg (70%) and SP >15–18 kg (70%) was like the adult donors with KDPI 30–85 (67%). In conclusion, we recommend single kidney transplants from SPDs with weight >12 kg to adult recipients in centers with experience in SPD transplants to optimize organ utilization.