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The aim of this study was to explore the roles of cytochrome P450 2E1 (CYP2E1) in 1,2‐dichloroethane (1,2‐DCE)‐induced liver damage. Two parts were included in this study: first, effect of 1,2‐DCE on microsomal expression of CYP2E1, and second, potential of an inhibitor of CYP2E1 to reduce 1,2‐DCE‐induced liver damage. In part one, mice were exposed to 0, 0.225, 0.45, or 0.9 g/m3 1,2‐DCE for 10 days,...
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