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Non‐technical summary The kidney plays a critical role in regulating body fluid volume and blood pressure by conserving ions, solutes and water. Knowing the processes that underpin the handling of ions, solutes and water by the kidney is essential to our understanding of fluid and blood pressure regulation. Movement of ions is mediated by specific transport proteins found in the membranes of kidney...
Non‐technical summary Gap junction channels formed from connexin (Cx) proteins are expressed in a variety of tissues providing exchange of metabolites and electrical communication between cells. We demonstrate that the uncoupling effects of gap junction channel blockers such as long carbon chain alkanols (LCCAs), volatile anaesthetics and the antimalarial drug mefloquine can be modulated by intracellular...
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