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Key points
Time‐restricted feeding (TRF, in which energy intake is restricted to 8 h/day during the dark phase) alone or combined with aerobic exercise (AE) training can prevent weight gain and metabolic disorders in Swiss mice fed a high‐fat diet.
The benefits of TRF combined with AE are associated with improved hepatic metabolism and decreased hepatic lipid accumulation.
TRF combined with AE training...
Key points
Afadin is a ubiquitously expressed scaffold protein with a recently discovered role in insulin signalling and glucose metabolism.
Insulin‐stimulated phosphorylation of Afadin at S1795 occurs in insulin‐responsive tissues such as adipose tissue, muscle, liver, pancreas and heart.
Afadin abundance and AfadinS1795 phosphorylation are dynamically regulated in metabolic tissues during diet‐induced...
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