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The protein corona effect has long been treated as the evil source behind delivery efficacy issues. In this study, this concept is challenged by showcasing that the protein corona can serve as a versatile functionalization approach to improve the delivery efficacy or mitigate nanocytotoxicity. To this end, the depleted serum is introduced to create nanomaterials carrying functionally distinct protein...
Osteosarcoma (OS) is one of the most common bone malignant tumors which mainly develops in adolescents. Although neoadjuvant chemotherapy has improved the prognosis of patients, numerous chemotherapeutic challenges still limit their use. Here, inspired by the Watson–Crick base pairing in nucleic acids, hydrophobic (methotrexate) and hydrophilic (floxuridine) chemo‐drugs are mixed and self‐assembled...
Breast Cancer Therapy
In article number 2201971, Ruibing Wang and co‐workers develop supramolecular peptide (based upon the host–guest interaction between cucurbit[7]uril and Phe‐Phe‐Val‐Leu‐Lys) capped Au nanocages, to allow self‐aggregation into micron‐sized clusters inside spermine‐overexpressed tumor cells, leading to specific accumulation and retention of Au nanocages in breast tumor for synergistic...
Wearable Pulsed Triboelectric Nanogenerators
In article number 2201056, Zhen Wen, Cao Yang, Yue Pan, and co‐workers fabricate a wearable pulsed triboelectric nanogenerator driven by human body movement, the triboelectric stimulation of which could reinforce osteogenesis of bone marrow mesenchymal stem cells (BMSCs) and promote angiogenesis of human umbilical vein endothelial cells by rejuvenating...
Alzheimer's disease (AD), as a progressive and irreversible brain disorder, remains the most universal neurodegenerative disease. No effective therapeutic methods are established yet due to the hindrance of the blood‐brain barrier (BBB) and the complex pathological condition of AD. Therefore, a multifunctional nanocarrier (Rapa@DAK/siRNA) for AD treatment is constructed to achieve small interfering...
Acute myocardial infarction (AMI) survivors face a high risk of mortality as a result of increasing heart failure and irreparable myocardial injury. New portable methods for immediate diagnosis must be developed to provide patients with daily warnings. Herein, the development of a dual‐mode photothermal‐pyroelectric output system based on a point‐of‐care platform for rapid AMI detection is reported...
Photoelectrochemical Water Splitting
In article number 2201410, Yi Zhu, Yongge Wei, and co‐workers show that due to the high proton conductivity of polyethylene glycol (PEG), protons can be transferred quickly out of H2O on the surface of PEG modified BiVO4 photoanodes to accelerate the formation of O2 gas during the splitting of water.
With the miniaturization of electronic‐based devices, the foreseen potential of new optical nanoprobes and the assessment of eventual size and shape effects, elaboration of multifunctional noncentrosymmetric nanocrystals with ferroelectric, pyroelectric, piezoelectric, and nonlinear optical properties are the subject of an increasing research interest. Here, the recent achievements from the solution‐based...
The high capacity of Li‐rich and Mn‐based (LRM) cathode materials is originally due to the unique hybrid anion‐ and cation redox, which also induces detrimental oxygen escape. Furthermore, the counter diffusion of released oxygen (into electrolyte) and induced oxygen vacancies (into the interior bulk phase) that occurs at the interface will cause uncontrolled phase collapse and other issues. Therefore,...
High‐capacity Ni‐rich layered oxides are considered as promising cathodes for lithium‐ion batteries. However, the practical applications of LiNi0.83Co0.07Mn0.1O2 (NCM83) cathode are challenged by continuous transition metal (TM) dissolution, microcracks and mixed arrangement of nickel and lithium sites, which are usually induced by deleterious cathode–electrolyte reactions. Herein, it is reported...
Developing highly active, durable, and cost‐effective electrocatalysts for the oxygen evolution reaction (OER) is of prime importance in proton exchange membrane (PEM) water electrolysis techniques. Ru‐based catalysts have high activities but always suffer from severe fading and dissolution issues, which cannot satisfy the stability demand of PEM. Herein, a series of iridium‐doped yttrium ruthenates...
Pre‐catalyst reconstruction in electrochemical processes has recently attracted intensive attention with mechanistic potentials to uncover really active species and catalytic mechanisms and advance targeted catalyst designs. Here, nickel‐molybdenum oxysulfide is deliberately fabricated as pre‐catalyst to present a comprehensive study on reconstruction dynamics for the oxygen evolution reaction (OER)...
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