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Nanocasting, using ordered mesoporous silica or carbon as a hard template, has enormous potential for preparing novel mesoporous materials with new structures and compositions. Although a variety of mesoporous materials have been synthesized in recent years, the growth mechanism of nanostructures in a confined space, such as mesoporous channels, is not well understood, which hampers the controlled...
Combination of optogenetics and pharmacology represents a unique approach to dissect neural circuitry with high specificity and versatility. However, conventional tools available to perform these experiments, such as optical fibers and metal cannula, are limited due to their tethered operation and lack of biomechanical compatibility. To address these issues, a miniaturized, battery‐free, soft optofluidic...
Despite great progress in lithium–sulfur batteries (LSBs), great obstacles still exist to achieve high loading content of sulfur and avoid the loss of active materials due to the dissolution of the intermediate polysulfide products in the electrolyte. Relationships between the intrinsic properties of nanostructured hosts and electrochemical performance of LSBs, especially, the chemical interaction...
Chemotherapy is the mainstream treatment of anaplastic large cell lymphoma (ALCL). However, chemotherapy can cause severe adverse effects in patients because it is not ALCL‐specific. In this study, a multifunctional aptamer‐nanomedicine (Apt‐NMed) achieving targeted chemotherapy and gene therapy of ALCL is developed. Apt‐NMed is formulated by self‐assembly of synthetic oligonucleotides containing...
To date, the possible depletion of lithium resources has become relevant, giving rise to the interest in Na‐ion batteries (NIBs) as promising alternatives to Li‐ion batteries. While extensive investigations have examined various transition metal oxides and chalcogenides as anode materials for NIBs, few of these have been able to utilize their high specific capacity in sodium‐based systems because...
Inspired by the hierarchically helical structure of classical thermal insulation material—wool, a stretchable heating carbon nanotube (CNT) fiber is created with excellent mechanical and heating properties. It can be stretched by up to 150% with high stability and reversibility, and a good thermal insulation is achieved from a large amount of formed hierarchically helical voids inside. Impressively,...
Atherosclerosis, driven by chronic inflammation of the arteries and lipid accumulation on the blood vessel wall, underpins many cardiovascular diseases with high mortality rates globally, such as stroke and ischemic heart disease. Engineered bio‐nanomaterials are now under active investigation as carriers of therapeutic and/or imaging agents to atherosclerotic plaques. This Review summarizes the latest...
Rapid clearance of nanoagents is a critical criterion for their clinical translation. Herein, it is reported that biodegradable and renal clearable nanoparticles are potentially useful for image‐guided photothermal therapy of tumors. The multifunctional nanoparticles with excellent colloidal stability are synthesized through coordination reactions between Fe3+ ions and gallic acid (GA)/polyvinyl pyrrolidone...
In article number 1702479, John A. Rogers, Jae‐Woong Jeong, and co‐workers develop a battery‐free, wireless optofluidic neural system by integrating a multimodal neural probe consisting of micro‐scale inorganic light‐emitting diodes, and a microfluidic drug delivery system with a stretchable radiofrequency energy‐scavenging circuit, into an ultracompact, lightweight and soft platform. The miniature...
In native tissues, cellular organization is predominantly anisotropic. Yet, it remains a challenge to engineer anisotropic scaffolds that promote anisotropic cellular organization at macroscopic length scales. To overcome this challenge, an innovative, cheap and easy method to align clinically approved non‐woven surgical microfibrillar scaffolds is presented. The method involves a three‐step process...
Ideal dimers comprising gold nanoparticles with a smooth surface and high sphericity are synthesized by a substrate‐based assembly strategy with efficient cetyltrimethylammonium bromide removal. An unprecedented structural and plasmonic uniformity at the single‐particle level is observed since inhomogeneities resulting from variations in gap morphology are eliminated. Single ideal dimers are analyzed...
In article number 1702650, Vahid Hosseini, Viola Vogel, and co‐workers present an innovative and cheap method to align 3D fibrillar scaffolds for surgical and tissue‐engineering applications. This easy to scale‐up method enables the creation of an aligned and highly porous 3D network of fibers with interconnected pores that are suitable for cell infiltration and alignment, both in vivo and in vitro...
Mitochondria‐mediated apoptosis (MMA) is a preferential option for cancer therapy due to the presence of cell‐suicide factors in mitochondria, however, low permeability of mitochondria is a bottleneck for targeting drug delivery. In this paper, glycyrrhetinic acid (GA), a natural product from Glycyrrhiza glabra, is found to be a novel mitochondria targeting ligand, which can improve mitochondrial...
In article number 1702754, Sebastian Schlücker and co‐workers synthesize ideal gold dimers of two spherical gold nanoparticles with a controlled gap distance and gap morphology. While theoreticians have been able to describe the properties of such a model system, experimentalists have failed to synthesize it. Here, elastic scattering of an ideal gold dimer using white light together with an electron...
Obtaining a wavelength division multiplexer (WDM) at the micro/nanometer level is a considerable challenge that holds great potential in optical communication technology owing to the enlarged data‐carrying capacity without laying more fibers. Of the progress that has been made in recent years, one of the most promising methods is to fabricate nanoscale pattern on silicon substrate, forcing signals...
Tungsten oxide (WO3) is an emerging 2D nanomaterial possessing unique physicochemical properties extending a wide spectrum of novel applications which are limited due to lack of efficient synthesis of high‐quality WO3. Here, a facile new synthetic method of forming WO3 from tungsten sulfide, WS2 is reported. Spectroscopic, microscopic, and X‐ray studies indicate formation of flower like aggregated...
Black phosphorus (BP) nanomaterials have emerged as rapidly rising stars in the field of nanomedicine. In this work, BP quantum dots (BPQDs) are synthesized and their potential as photosensitizers is investigated for the first time. The BPQDs present good stability in physiological medium and no appreciable cytotoxicity. More importantly, the BPQDs can be rapidly eliminated from the body in their...
Infectious diseases are caused by pathogenic microorganisms and are often severe. Time to fully characterize an infectious agent after sampling and to find the right antibiotic and dose are important factors in the overall success of a patient's treatment. Previous results suggest that a nanomotion detection method could be a convenient tool for reducing antibiotic sensitivity characterization time...
Optical techniques for molecular diagnostics or DNA sequencing generally rely on small molecule fluorescent labels, which utilize light with a wavelength of several hundred nanometers for detection. Developing a label‐free optical DNA sequencing technique will require nanoscale focusing of light, a high‐throughput and multiplexed identification method, and a data compression technique to rapidly identify...
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