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Precise quantification of intracellular iron contents is important to biomedical applications of magnetic nanoparticles. Current approaches for iron quantification rely on specialized instruments while most only yield iron quantities averaged over plenty of cells. Here, a simple and robust approach, combining digital optical microscopy with the Beer–Lambert's law, that allows for imaging stainable...
In article number 2005474, Qi‐Huo Wei, Ning Gu, and co‐workers show that by combining the Beer‐Lambert's law with digital optical microscopy, iron contents in individual cells can be imaged and quantified with high accuracy, better than femtogram per pixel. This technique can be deployed easily in research and clinical labs for studying biomedical applications of magnetic nanoparticles and disease...
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