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Bismuth ferrite harmonic nanoparticles (BFO‐HNPs) are a non‐linear material capable of second‐harmonic generation (SHG). In article number 1803776, Fernanda Ramos‐Gomes, Marietta Andrea Markus, and co‐workers use BFO‐HNPs to visualize macrophages in the lungs of mice with allergic airway inflammation. Using multiphoton microscopy, the intense SHG signals from BFO‐HNPs can track macrophages in the...
Recently, second harmonic generation (SHG) nanomaterials have been generated that are efficiently employed in the classical (NIR) and extended (NIR‐II) near infrared windows using a multiphoton microscope. The aim was to test bismuth ferrite harmonic nanoparticles (BFO‐HNPs) for their ability to monitor pulmonary macrophages in mice. BFO‐loaded MH‐S macrophages are given intratracheally to healthy...
Here, amorphous silica nanoparticles (NPs), one of the most abundant nanomaterials, are used as an example to illustrate the utmost importance of surface coverage by functional groups which critically determines biocompatibility. Silica NPs are functionalized with increasing amounts of amino groups, and the number of surface exposed groups is quantified and characterized by detailed NMR and fluorescamine...
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