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Due to their various potential biomedical applications, hydrogels based on engineered proteins have attracted considerable interest. Benefitting from significant progress in recombinant DNA technology and protein engineering/design techniques, the field of protein hydrogels has made amazing progress. The latest progress of hydrogels constructed from engineered recombinant proteins are presented, mainly...
The combination of bottom‐up controllable self‐assembly technique with bioinspired design has opened new horizons in the development of self‐propelled synthetic micro/nanomotors. Over the past five years, a significant advances toward the construction of bioinspired self‐propelled micro/nanomotors has been witnessed based on the controlled self‐assembly technique. Such a strategy permits the realization...
The synthesis of mesoporous nanoparticles with controllable structure and organic groups is important for their applications. In this work, yolk–shell‐structured periodic mesoporous organosilica (PMO) nanoparticles simultaneously incorporated with ethane‐, thioether‐, and benzene‐bridged moieties are successfully synthesized. The preparation of the triple‐hybridized PMOs is via a cetyltrimethylammonium...
On page 3550, G. Lu, L. Wang, and co‐workers report yolk–shell structured periodic mesoporous organosilica (PMO) nanoparticles simultaneously incorporated with ethane, thioether, and benzene moieties. The unique yolk–shell structure is formed via hydrothermal treatment of triple‐hybridized PMOs synthesized using a surfactant‐directed sol–gel process. Excellent biobehaviors, bioimaging properties,...
Pickering emulsions, stabilized by various micro‐ or nanoparticles with different structures, morphologies or other characteristics, possess distinctive properties and versatile functions comparing with classical emulsions stabilized by surfactants. In recent years their applications, especially in the biomedical field, have been carried out extensively and widely such as templates to prepare colloidosomes,...
In recent years, emulsions stabilized by micro‐ or nanoparticles (known as Pickering emulsions) have attracted much attention. Micro‐ or nanoparticles, as the main components of the emulsion, play a key role in the preparation and application of Pickering emulsions. The existence of particles at the interface between the oil and aqueous phases affects not only the preparation, but also the properties...
During recent decades, a giant leap in the development of nanotechnology has been witnessed. Numerous nanomaterials with different dimensions and unprecedented features have been developed and provided unimaginably wide scope to solve the challenging problems in biomedicine, such as cancer diagnosis and therapy. Recently, two‐dimensional (2D) transition metal dichalcogenide (TMDC) nanosheets (NSs),...
As a new kind of 2D material, black phosphorus has gained increased attention in the past three years. Although few‐layered black phosphorus nanosheets (BPs) degrade quickly under ambient conditions to phosphate anions, which greatly hampers their optical and electronic applications, this property also makes BPs highly biocompatible and biodegradable, and is regarded as an advantage for various biomedical...
Catalytic nanomaterials can be used extrinsically to combat diseases associated with a surplus of reactive oxygen species (ROS). Rational design of surface morphologies and appropriate doping can substantially improve the catalytic performances. In this work, a class of hollow polyvinyl pyrrolidone‐protected PtPdRh nanocubes with enhanced catalytic activities for in vivo free radical scavenging is...
Due to their unique optical properties, diamonds are the most valued gemstones. However, beyond the sparkle, diamonds have a number of unique properties. Their extreme hardness gives them outstanding performance as abrasives and cutting tools. Similar to many materials, their nanometer‐sized form has yet other unique properties. Nanodiamonds are very inert but still can be functionalized on the surface...
In article number 1906184, Yingfeng Tu, Fei Peng, and co‐workers highlight the recent progress of biocompatible micro‐/nanomotor systems and their applications in the biomedical field. By summarizing the effort that has been made for the biocompatibility of micro‐/nanomotors during the past decade, it is expected that the real‐world application of micro‐/nanomotors in biomedicine will be further developed...
Inspired by the highly versatile natural motors, artificial micro‐/nanomotors that can convert surrounding energies into mechanical motion and accomplish multiple tasks are devised. In the past few years, micro‐/nanomotors have demonstrated significant potential in biomedicine. However, the practical biomedical applications of these small‐scale devices are still at an infant stage. For successful...
Micro/nanomotors (MNMs) are miniaturized machines that can perform assigned tasks at the micro/nanoscale. Over the past decade, significant progress has been made in the design, preparation, and applications of MNMs that are powered by converting different sources of energy into mechanical force, to realize active movement and fulfill on‐demand tasks. MNMs can be navigated to desired locations with...
2D nanomaterials (2DNMs) possess fascinating properties and are found in multifarious devices and applications including energy storage devices, new generation of battery technologies, sensor devices, and more recently in biomedical applications. Their use in biomedical applications such as tissue engineering, photothermal therapy, neural regeneration, and drug delivery has opened new horizons in...
Potential biomedical applications of gold nanoparticles have increasingly been reported with great promise for diagnosis and therapy of several diseases. However, for such a versatile nanomaterial, the advantages and potential health risks need to be addressed carefully, as the available information about their toxicity is limited and inconsistent. Atomically precise gold nanoclusters (AuNCs) have...
In article number 2005499, María Francisca Matus and Hannu Häkkinen discuss the recent advances for using atomically precise gold nanoclusters for biomedical applications and their advantages over the well‐known colloidal gold nanoparticles. The ultrasmall size and monodispersity of gold nanoclusters are key factors for their excellent biocompatibility and show great potential for designing a new...
In the last years, cancer immunotherapy has started to attract a lot of attention, becoming one of the alternatives in the clinical treatment of cancer. Indeed, one of the advantages of immunotherapy is that both primary and distant tumors can be efficiently eradicated through a triggered immune response. Due to their large specific surface area and unique physicochemical properties, 2D materials...
Graphene quantum dot (GQD) is one of the youngest superstars of the carbon family. Since its emergence in 2008, GQD has attracted a great deal of attention due to its unique optoelectrical properties. Non‐zero bandgap, the ability to accommodate functional groups and dopants, excellent dispersibility, highly tunable properties, and biocompatibility are among the most important characteristics of GQDs...
Plants are anatomically and physiologically different from humans and animals; however, there are several possibilities to utilize the unique structures and physiological systems of plants and adapt them to new emerging technologies through a strategic biomimetic approach. Moreover, plants provide safe and sustainable results that can potentially solve the problem of mass‐producing practical materials...
Taking inspiration from the extremely flexible motion abilities in natural organisms, soft actuators have emerged in the past few decades. Particularly, smart film actuators (SFAs) demonstrate unique superiority in easy fabrication, tailorable geometric configurations, and programmable 3D deformations. Thus, they are promising in many biomedical applications, such as soft robotics, tissue engineering,...
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