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On page 6076, D. Therriault and co‐workers demonstrate a 3D printing method used to make a liquid sensor with a potential application in oil industry. The cover image shows a 3D printing machine printing a scaffold structure around a pipeline joint with an electronic device as a leak detector on top of the joint. The background is a SEM image of a 3D printed scaffold, used as a liquid sensor.
The utilization of 3D printing of highly conductive (σ ≈ 2350 S m−1) polymer composite structures for the functional optimization of scaffold‐shaped liquid sensors is demonstrated. This study can open the pathway of the application of 3D printing of conductive composites for optimization of structures useful for various applications such as smart sensors in textile or in the field of electronics....
In article number 1700550, Martin Andersson and co‐workers, report a new method to form multiscale, bioinspired composite materials by combining bottom‐up molecular self‐assembly and top‐down additive manufacturing. The composites are ordered constructs with an organic‐inorganic interpenetrating nanostructure aligned over centimeter length‐scales, with structural features as small as 10 nm. The composites...
Biological composites display exceptional mechanical properties owing to a highly organized, heterogeneous architecture spanning several length scales. It is challenging to translate this ordered and multiscale structural organization in synthetic, bulk composites. Herein, a combination of top‐down and bottom‐up approach is demonstrated, to form a polymer‐ceramic composite by macroscopically aligning...
The present work reports the first demonstration of straightforward fabrication of monolithic unibody lab‐on‐a‐chip (ULOCs) integrating bioactive micrometric 3D scaffolds by means of multimaterial stereolithography (SL). To this end, a novel biotin‐conjugated photopolymer is successfully synthesized and optimally formulated to achieve high‐performance SL‐printing resolution, as demonstrated by the...
One of the basic operations in microfluidic systems for biological and chemical applications is the rapid mixing of different fluids. However, flow profiles in microfluidic systems are laminar, which means molecular diffusion is the only mixing effect. Therefore, mixing structures are crucial to enable more efficient mixing in shorter times. Since traditional microfabrication methods remain laborious...
Nanoporous metals represent a class of functional materials with unique bicontinuous open porous structural properties, making them ideal candidates for various catalyst applications. However, the pursuit of nanoporous properties, extremely small pores, and high surface area, results in the restriction of mass transport. Herein, a free‐standing hierarchical nanoporous Cu material, prepared by a selective...
Skeletal muscle tissue engineering (SMTE) aims at repairing defective skeletal muscles. Until now, numerous developments are made in SMTE; however, it is still challenging to recapitulate the complexity of muscles with current methods of fabrication. Here, after a brief description of the anatomy of skeletal muscle and a short state‐of‐the‐art on developments made in SMTE with “conventional methods,”...
Heart valves are characterized to be highly flexible yet tough, and exhibit complex deformation characteristics such as nonlinearity, anisotropy, and viscoelasticity, which are, at best, only partially recapitulated in scaffolds for heart valve tissue engineering (HVTE). These biomechanical features are dictated by the structural properties and microarchitecture of the major tissue constituents, in...
Electrically conductive materials that mimic physical and biological properties of tissues are urgently required for seamless brain–machine interfaces. Here, a multinetwork hydrogel combining electrical conductivity of 26 S m−1, stretchability of 800%, and tissue‐like elastic modulus of 15 kPa with mimicry of the extracellular matrix is reported. Engineering this unique set of properties is enabled...
This cover shows Tubulane structures made up of bio‐degradable soft polymer created by 3D printing. It can handle ballistic impact. The bullet stops in the second layer of the tubulane structure with no significant structural damage while bullet fire with the same speed propagates the crack through the whole reference cube. More details can be found in article number 1904747 by Douglas S. Galvão,...
Lightweight materials with high ballistic impact resistance and load‐bearing capabilities are regarded as a holy grail in materials design. Nature builds these complementary properties into materials using soft organic materials with optimized, complex geometries. Here, the compressive deformation and ballistic impact properties of three different 3D printed polymer structures, named tubulanes, are...
Scanning‐probe microscopy (SPM) is the method of choice for high‐resolution imaging of surfaces in science and industry. However, SPM systems are still considered as rather complex and costly scientific instruments, realized by delicate combinations of microscopic cantilevers, nanoscopic tips, and macroscopic read‐out units that require high‐precision alignment prior to use. This study introduces...
Direct mass‐transfer via liquid nanodroplets is one of the most powerful approaches for additive micro/nanofabrication. Electrohydrodynamic (EHD) dispensing has made the delivery of nanosized droplets containing diverse materials a practical reality; however, in its serial form it has insufficient throughput for large‐area processing. Here, a parallel, nanoscale EHD method is developed that offers...
Improving productivity and material diversity is a key challenge for 3D printing to become a true manufacturing platform. In article number 1906402, Ji Tae Kim and co‐workers develop a parallel electrohydrodynamic 3D nanoprinting method for functional materials. The method exploits an unusual electric field distribution created by cross talk of neighboring printing nozzles to steer the ejection paths...
In article number 1906539, Yi Hong, Hongwei Ouyang, and co‐workers establish an “all‐in‐one” gel microsphere‐based system for stem cell amplification and tissue engineering, including enhanced cell expansion, convenient and harmless passage, quick and complete harvest, efficient cryopreservation and transportation, as well as functional macro‐tissue construction. The gel microspheres are fabricated...
Soft lithography enables rapid microfabrication of many types of microsystems by replica molding elastomers into master molds. However, master molds can be very costly, hard to fabricate, vulnerable to damage, and have limited casting life. Here, an approach for the multiplication of master molds into monolithic thermoplastic sheets for further soft lithographic fabrication is introduced. The technique...
Microsphere (MS)‐based systems provides great advantages for cell expansion and transplantation due to their high surface‐to‐volume ratio and biomimetic environment. However, a MS‐based system that includes cell attachment, proliferation, passage, harvest, cryopreservation, and tissue engineering together has not been realized yet. An “all‐in‐one” gel MS‐based system is established for human adipose‐derived...
High temperature synthesis and treatments are ubiquitous in chemical reactions and material manufacturing. However, conventional sintering furnaces are bulky and inefficient with a narrow temperature range (<1500 K) and slow heating rates (<100 K min−1), which are undesirable for many applications that require transient heating to produce ideal nanostructures. Herein, a 3D‐printed, miniaturized...
In article number 1906259, Petra Schwille and co‐workers demonstrate 3D printing of a microscale device made of a biocompatible protein hydrogel that can be used to induce reversible shape changes in trapped vesicles by pH‐stimulus. These soft material‐based cages provide an artificial microenvironment, which may in the future allow us to investigate how synthetic cells react to and interact with...
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