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Recruitment of receptors at membrane interfaces is essential in biological recognition and uptake processes. The interactions that induce recruitment are typically weak at the level of individual interaction pairs, but are strong and selective at the level of recruited ensembles. Here, a model system is demonstrated, based on the supported lipid bilayer (SLB) that mimics the recruitment process induced...
Receptor Recruitment
Ligand‐functionalized lipid vesicles bind to receptor‐functionalized supported lipid bilayers through weak, multivalent receptor‐ligand interactions. As a result of binding, surface‐bound receptors move into the area of contact – a process called “recruitment” – to increase the local receptor density and thus enhance binding. The affinity, the size and the receptor density of...
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