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The principal site for gaseous exchange within the lung is the alveolar space, which is bathed in a lipid‐protein blend called pulmonary surfactant. This material is the initial contacting site for orally inhaled products and environmental toxins. Using the lung biosimulator, this study investigates the influence of cannabis smoke on the activity of the lung surfactant replacement product, Curosurf...
Drug delivery to the body via the inhaled route is dependent upon patient status, device use, and respirable formulation characteristics. Further to inhalation, drug‐containing particles interact and dissolve within pulmonary fluid leading to the desired pharmacological response. Pulmonary surfactant stabilises the alveolar air‐liquid interface and permits optimal respiratory mechanics. This material...
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