The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The optimal dose of targeted treatment in oncology may not be the maximal tolerated dose. Evaluating jointly toxicity and efficacy data is then desirable. We propose an adaptive dose finding approach to identify a dose based on repeated binary toxicity and continuous efficacy outcomes from the first two cycles. Probit and linear Gaussian models are used for the toxicity and efficacy at each cycle...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.