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Bone defect is an important topic in public health. Novel therapies are based on osteogenic induction by natural antiosteoporotic compounds including plant‐derived estrogens. In the current study, the osteogenic potential of Sophora pachycarpa root extract (SPRE) was explored on human adipose‐derived mesenchymal stem cells. Herein, adipose‐derived mesenchymal stem cells were osteoinducted in the presence...
To reach ideal therapeutic potential of stem cells for regenerative medicine purposes, it is essential to retain their self‐renewal and differentiation capacities. Currently, biological factors are extensively used for stemness maintaining and differentiation induction of stem cells. However, low stability, high cost, complicated production process, and risks associated with viral/endotoxin infection...
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