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In this report, we describe the X‐ray crystal structures of two single domain camelid antibodies (VHH), F5 and F8, each in complex with ricin toxin's enzymatic subunit (RTA). F5 has potent toxin‐neutralizing activity, while F8 has weak neutralizing activity. F5 buried a total of 1760 Å2 in complex with RTA and made contact with three prominent secondary structural elements: α‐helix B (Residues 98–106),...
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