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A historic challenge for shotgun proteomics has been the requirement for high quality, simple, and nonredundant curated protein sequences in small .fasta text files. Due to the intrinsic informatic challenges and time required to assemble these files, proteomics has struggled to expand beyond the confines of a few model organisms. When considering post‐translational modifications that may or may not...
Protein glycosylation is increasingly recognized as a common protein modification across bacterial species. Within the Neisseria genus O‐linked protein glycosylation is conserved yet closely related Neisseria species express O‐oligosaccharyltransferases (PglOs) with distinct targeting activities. Within this work, we explore the targeting capacity of different PglOs using Field Asymmetric Waveform...
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