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Paucimannosidic N‐glycans (PMGs) are special in that they only have the chitobiose core of two β‐linked N‐acetylglucosamines extended with up to three mannose residues and a core fucose. While such short‐chain glycans are well described in plants, reports on their expression in humans have been rather scarce. Also, these glycans are often seen as a potential analytical artifact. Recently, it became...
While aberrant protein glycosylation is a recognized characteristic of human cancers, advances in glycoanalytics continue to discover new associations between glycoproteins and tumorigenesis. This glycomics‐centric study investigates a possible link between protein paucimannosylation, an under‐studied class of human N‐glycosylation [Man1‐3GlcNAc2Fuc0‐1], and cancer. The paucimannosidic glycans (PMGs)...
Colorectal cancer (CRC) affects both women and men living in societies with a high sedentary lifestyle. Amongst the phenotypic changes exhibited by tumor cells, a wide range of glycosylation has been reported for colon cancer‐derived cell lines and CRC tissues. These aberrant modifications affect different aspects of glycosylation, including an increase in core fucosylation and GlcNAc branching on...
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