DOI: 10.1002/pmic.201700092
Salmonella infection is a great model system to study host‐pathogen interactions. Quantitative proteomics analysis of Salmonella‐infected epithelial cells revealed that host integrin proteins and glycolytic pathways were markedly induced while nuclear RNA metabolism proteins were down‐regulated. Importantly, we found higher levels of nuclear PARP1 in infected cells, an event likely specific to Salmonella infection. This work demonstrates that unbiased high‐throughput proteomics can be used as a powerful approach to provide new perspectives on host‐pathogen interactions. For more details, see the research article by Linlu Qi et al., article number 1700092.