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Objective
Sacubitril/valsartan (SAC/VAL) has been shown to reduce mortality and hospitalization in patients with heart failure with reduced ejection fraction (HFrEF) compared with enalapril but at a substantially higher cost. This study evaluates the cost‐effectiveness of SAC/VAL versus enalapril in patients with HFrEF over a 5‐year time horizon from the U.S. payer perspective.
Methods
A cohort‐based...
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