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BackgroundIkaros, the product of IKZF1, is a regulator of lymphoid development and polymorphisms in the gene have been associated with the acute lymphoblastic leukemia (ALL). Additionally, IKZF1 deletions and mutations identify high‐risk biological subsets of childhood ALL [Georgopoulos et al. Cell 1995;83(2):289–299; Mullighan et al. N Engl J Md 2009;360(5):470–480].
ProceduresTo discover the underlying...
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