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Giant cell tumour of bone (GCTB) comprises the eponymous osteoclastic multinucleated giant cells eliciting bone lysis, an H3F3A‐mutated neoplastic mononucleated fibroblast‐like cell population, and H3F3A wild‐type mononucleated stromal cells. In this study, we characterised four new cell lines from GCTB. Furthermore, we compared the genome‐wide DNA methylation profile of 13 such tumours and three...
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