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Background
The major symptoms of irritable bowel syndrome (IBS) are changes in bowel habits and abdominal pain. Psychological stress is the major pathophysiological components of IBS. Corticotropin‐releasing factor (CRF) is a well‐known integrator in response to psychological stress. In this study, a novel CRF1 receptor antagonist T‐3047928 was evaluated in stress‐induced IBS models of rats to explore...
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