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Aims
There have been few reports on whether long‐term oral phosphodiesterase 5 inhibitor administration can ameliorate bladder changes due to bladder outlet obstruction (BOO). Therefore, we clarified the chronological changes of the bladder using male BOO rats and evaluated the effects of tadalafil on these changes.
Methods
Eight‐week‐old male Sprague‐Dawley rats were used. BOO was created by placing...
Aims
Though the pressure‐volume analysis (PVA), a method based on thermodynamics, is broadly used for assaying cardiac functions, its potential application on the physiology/pathophysiology of the urinary bladder, which processes resemble thermodynamic cycles to the heart, has not been established.
Methods
Cystometry recording intravesical pressure (IVP) and intravesical volume (IVV) of rhythmic...
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