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AimsThe paired box gene 8 (PAX8) plays crucial roles in organ patterning and cellular differentiation during development and tumorigenesis. Although its function is partly understood in vertebrate development, there is poor data concerning human central nervous system (CNS) development and brain tumours.
MethodsWe investigated developing human (n = 19) and mouse (n = 3) brains as well as medulloblastomas...
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