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Purpose
To compare different optimization approaches for choosing the spin‐lock times (TSLs), in spin‐lattice relaxation time in the rotating frame (T1ρ) mapping.
Methods
Optimization criteria for TSLs based on Cramér‐Rao lower bounds (CRLB) are compared with matched sampling‐fitting (MSF) approaches for T1ρ mapping on synthetic data, model phantoms, and knee cartilage. The MSF approaches are optimized...