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Although the biasing of
R*2 estimates by assuming magnitude MR data to be normally distributed has been described, the effect on changes in R*2 (ΔR*2), such as induced by a paramagnetic contrast agent, has not been reported. In this study, two versions of a novel Bayesian maximum a posteriori approach for estimating ΔR*2 are described and evaluated: one that assumes normally distributed data and the...
The spatial distribution of apparent diffusion coefficient (ADC) estimates in tumors is typically heterogeneous, although this observed variability is composed of both true regional differences and random measurement uncertainty. In this study, an adaptive Bayesian adaptive smoothing (BAS) model for estimating ADC values is developed and applied to data acquired in two murine tumor models in vivo...
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