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Purpose
To develop a method that fits a multipool model to z‐spectra acquired from non–steady state sequences, taking into account the effects of variations in T1 or B1 amplitude and the results estimating the parameters for a four‐pool model to describe the z‐spectrum from the healthy brain.
Methods
We compared measured spectra with a look‐up table (LUT) of possible spectra and investigated the...
Purpose
To quantify amide protein transfer (APT) effects in acidic ischemic lesions and assess the spatial‐temporal relationship among diffusion, perfusion, and pH deficits in acute stroke patients.
Methods
Thirty acute stroke patients were scanned at 3 T. Quantitative APT (APT#) effects in acidic ischemic lesions were measured using an extrapolated semisolid magnetization transfer reference signal...
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