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Scope
Obesity increases intracellular lipid accumulation in hepatocytes, which can induce non‐alcoholic fatty liver disease (NAFLD). With progression of NAFLD, a sizable fraction of patients develop non‐alcoholic steatohepatitis (NASH), eventually leading to cirrhosis and hepatocellular carcinoma (HCC). The mechanism involved in obesity‐induced NAFLD remains unclear. Free fatty acids and high‐fat...
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