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Non‐small cell lung cancer (NSCLC) is characterized by poor prognosis and only a few molecular markers may be potentially used to predict the risk of progression. This study aims to assess the effects of single nucleotide polymorphisms (SNPs) in the CD98 gene on prognosis of NSCLC patients. We genotyped three potential functional SNPs in CD98 gene using Sequenom iPLEX genotyping system in a cohort...
Metallothioneins (MTs) are cysteine‐rich proteins that act as antioxidants. A case‐control study was conducted to assess the effects of gene polymorphisms in the MT region on the risk of lung cancer in Japanese subjects: 769 lung cancer cases and 939 non‐cancer controls. Associations were evaluated using logistic regression models with adjustment for potential confounders (age, sex, and lifestyle...
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