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A number of highly abundant proteins in urine have been identified through proteomics approaches, and some have been considered as disease‐biomarker candidates. These molecules might be clinically useful in diagnosis of various diseases. However, none has proven to be specifically indicative of perturbations of cellular processes in cells associated with urogenital diseases. Exosomes could be released...
Cataract, the opacification of the eye lens, is the leading cause of blindness worldwide—it accounts for approximately 42% of all cases. The lens fibers have the highest protein content within the body, more than 35% of their wet weight. Given the eye lens pure composition of highly abundant structural proteins crystallins (up to 90%), it seems to be an ideal proteomic entity to study and might be...
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