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Multicomponent insulin‐containing microparticles are prepared by layer‐by‐layer assembly of dextran sulfate and chitosan on the core of protein‐polyanion complex with or without protease inhibitors. Oral bioavailability of the encapsulated insulin is improved due to the cumulative effect of each component. A physico‐chemical study shows that the particle design allows adjustment of the pH‐dependent...
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