The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Two pH‐activatable star‐shaped prodrugs are synthesized through the condensation reaction between Y‐ or dumbbell‐shaped poly(ethylene glycol)‐poly(lactic acid‐co‐glycolic acid) (PEG‐PLGA) copolymer and acid‐sensitive cis‐aconityl‐doxorubicin. The prodrugs self‐assemble into micelles with favorable hydrodynamic radii and relatively low critical micelle concentrations. In vitro DOX release from prodrug...
Two copolymers are designed and synthesised for siRNA delivery based on polyethylenimine by grafting hydrophilic acrylamide segments and hydrophobic poly(γ‐benzyl L‐glutamate). The amphiphilic PEI‐PBLG/siRNA complex demonstrates high gene silencing efficiency in the absence or presence of 10 vol% and 50 vol% sera in vitro. The anti‐tumor effects in vivo are evaluated in luciferase‐bearing mice expressing...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.