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The effect of converting ammonium into guanidine moieties, compared to other factors such as molecular weight or hydrophobicity, on the antibacterial activity is investigated for homo‐ and copolymers of 2‐aminoethylmethacrylate in solution or coatings. Polymers are obtained by free radical polymerization, polymer‐analogous guanidinylation is conducted with cyanamide; non‐leaching immobilization is...
In spite of their attractive features, widespread biomedical applications of CS nanoparticles are yet to be realized due to their poor stability in physiological conditions, such as in buffer system at pH 7.4. Buffer‐stable chitosan‐based hybrid NPs (HNPs) are reported and characterized. Buffer stability is achieved by introducing polyglutamic acid to chitosan. The effect of PGA to CS molar ratio...
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