Front Cover:On page 632, G. Ciofani and team report a microparticle system based on a recombinant human elastin‐like polypeptide (HELP) for drug delivery applications. HELP microparticles are prepared through a water‐in‐oil emulsion of an aqueous solution of recombinant polypeptide in isoctane, followed by enzymatic cross‐linking. Superparamagnetic iron oxide nanoparticles are introduced to confer magnetic properties to the microspheres, thus controlling their targeting and tracking as drug vectors. The obtained microparticles are characterized in terms of morphology, structure, magnetic properties, drug release, and magnetic drivability, showing promise for further biomedical applications.