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Background
Severe hepatic steatosis shows a high prevalence and contributes to morbidity and mortality in human immunodeficiency virus (HIV) infected patients. Known risk factors include obesity, dyslipidaemia and features of metabolic syndrome. Fibroblast growth factor 21 (FGF‐21) is involved with hepatic glucose and lipid metabolism. This study aimed to evaluate FGF‐21 as a biomarker for severe...
Background/aims
Non‐invasive fibrosis tests (NITs) can be used to triage non‐alcoholic fatty liver disease (NAFLD) patients at risk of advanced fibrosis (AF). We modelled and investigated the diagnostic accuracy and costs of a two‐tier NIT approach in primary care (PC) to inform secondary care referrals (SCRs).
Methods
A hypothetical cohort of 1,000 NAFLD patients with a 5% prevalence of AF was...
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