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Sleep has been postulated to promote brain energy restoration. It is as yet unknown if increasing the energy availability within the brain reduces sleep need. The guanidine amino acid creatine (Cr) is a well‐known energy booster in cellular energy homeostasis. Oral Cr–monohydrate supplementation (CS) increases exercise performance and has been shown to have substantial effects on cognitive performance,...
Sleep—or sleep‐like states—have been reported in adult and larval zebrafish using behavioural criteria. These reversible quiescent periods, displaying circadian rhythmicity, have been used in pharmacological, genetic and neuroanatomical studies of sleep–wake regulation. However, one of the important criteria for sleep, namely sleep homeostasis, has not been demonstrated unequivocally. To study rest...
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