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The objective of this study was to evaluate near infrared (NIR) spectroscopy and imaging as approaches to assess drug contents in poly(dl‐lactide‐co‐glycolide) (PLGA) based nanoparticles of a model protein, cyclosporine A (CyA). A 6‐factors 12‐runs designed set of experiments with Plackett–Burman (PB) screening was applied in order to examine the effects of drug loading (X1), polymer loading (X2),...
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