Aim
The aim of this study was to determine clinical performance of gestrinone combined with ultrasound‐guided aspiration and ethanol injection in treating chocolate cyst of ovary.
Methods
Sixty‐eight patients enrolled in this study were randomly divided into two groups: control group and combination treatment group. In the control group, 34 patients were treated with ultrasound‐guided aspiration and ethanol injection. In the combination treatment group, 34 patients received gestrinone p.o. following ultrasound‐guided aspiration and ethanol injection.
Results
The recurrence rate of chocolate cyst was 10‐fold lower in the combination treatment group (2.94%, 1/34) than in the control group (29.4%, 10/34) at 12 months. The effective rate for reduction of chocolate cyst was significantly higher in the combination treatment group (94.12%, 32/34) than in the control group (64.71%, 22/34) (P = 0.009).
Conclusion
Gestrinone combined with ultrasound‐guided aspiration and ethanol injection therapy is an effective treatment for ovarian chocolate cyst with low recurrence rate.