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The glutamate‐nitric oxide (NO)‐cGMP pathway modulates some forms of learning. How glycine modulates this pathway is unclear. Glycine could modulate the pathway biphasically, enhancing its function through NMDA receptor activation or reducing it through glycine receptor activation. Chronic hyperammonemia impairs the glutamate‐NO‐cGMP pathway in the cerebellum and induces cognitive impairment. The...
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