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J. Neurochem. (2012) 122, 456–469.
AbstractOxidative stress and neuroinflammation play important roles in Alzheimer’s disease (AD). ABCG2 is a transporter protein expressed in the brain and involved in GSH transport. To study the roles of Abcg2 in oxidative stress and AD, we cross‐bred Tg‐SwDI and Abcg2‐KO mice and generated Tg‐SwDI/Abcg2‐KO (double‐tg) mice. Brain tissues from double‐tg, Tg‐SwDI,...
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