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ObjectivesTo determine safety and tolerability of lowering blood pressure in older adults with lacunar stroke.
DesignCohort study.
SettingThe Secondary Prevention of Small Subcortical Strokes (SPS3) Trial, which compared the efficacy of two systolic blood pressure (SBP) targets (<130 mmHg and 130–149 mmHg) for secondary stroke prevention.
ParticipantsOf 3,020 SPS3 participants, 494 aged 75 and...
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