Journal of the European Academy of Dermatology and Venereology
Background Atopic dermatitis (AD) is a common inflammatory skin disease. Methotrexate (MTX) was suggested as an effective treatment option in cases of moderate‐to‐severe atopic dermatitis. This study assessed the efficacy and safety of treatment with low weekly doses of methotrexate for moderate‐to‐severe AD in adults.
Methods Twenty adult patients with moderate‐to‐severe AD were included in this...
Background Ultraviolet B (UVB) is a well‐known modality in increasing skin pigmentation through a variety of proposed mechanisms. Prostaglandin release is one of these mechanisms. Prostaglandin F2α (PGF2α) analogues, which are used to control ocular hypertension, were reported to induce periocular skin hyperpigmentation.
Objectives This study aims to evaluate the local effect of three prostaglandin...
Background Monitoring and repeated staging is of substantial importance in many patients with primary cutaneous T‐cell lymphomas (CTCL). For primary cutaneous B‐cell lymphomas (CBCL), extensive initial staging is the mainstay for correct diagnosis.
Aim To evaluate the value of somatostatin receptor scintigraphy using the radiolabeled somatostatin analog 111In‐pentetreotide in comparison to conventional...
Background The chronic and treatment‐resistant nature of nail psoriasis affects patients’ lives not only physically but also psychologically. Although there are scoring systems available for disease severity, there is as yet no scale to evaluate the impact of this condition upon the patients’ quality of life.
Objectives This study aims to develop and validate a quality of life scale specifically...
Background Juvenile bullous pemphigoid (JBP) is a very rare autoimmune blistering disease. Up to now, 81 cases have been published.
Objectives To describe clinical, histopathological and immunopathological characteristics of our patients with JBP, their response to therapy and clinical course, and to show the rarity of JBP in our population.
Study design Retrospective study of all patients with...
Background Skin tags are common benign lesion occurring mainly on the neck and major flexures as a small soft pedunculated protrusion. This study evaluate insulin and insulin‐like growth factor‐I (IGF‐I) in non‐diabetic ones.
Methods and materials A case–control study was conducted in non‐diabetic persons. Comparing insulin and IGF‐I between matched cases (n = 40) and controls (n = 40) by radioimmunoassay...
Backround Pemphigus vulgaris is a rare chronic autoimmune disease of skin and mucous membranes, with several cytokines participating in its development. The role of their gene polymorphisms in susceptibility to the disease is, however, not fully understood.
Objective The aim of our case‐control study was to investigate whether some of 22 single nucleotide polymorphisms (SNPs) in 13 cytokine genes...