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Treatment non‐adherence is a general challenge and a complex problem. It is a key factor that impacts the ‘real‐life’ effectiveness of topical treatments for chronic disorders, such as psoriasis. Here, we provide our expert opinion on the real‐life effectiveness of topical psoriasis treatment, using the fixed combination gel (Daivobet® gel; calcipotriol plus betamethasone dipropionate) as a case study...
The fixed combination calcipotriol plus betamethasone dipropionate gel is a first‐line treatment for psoriasis vulgaris. The objective was to perform a large‐scale assessment of tolerability of fixed combination gel (Cal/BD). Analysis was performed on pooled 8‐week safety data from nine clinical trials evaluating once‐daily Cal/BD treatment of scalp (n =6) and body (n =3) psoriasis. Pharmacovigilance...
Psoriasis is a chronic, recurrent immune‐mediated skin disease with a 2–3% prevalence in the Western population, which severely affects patients’ quality of life and poses a considerable socioeconomic challenge. The majority of individuals have psoriasis in limited areas and topical products are the mainstay of therapy according to existing guidelines. It is known that medication adherence rates are...
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