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In this study, the wound healing properties of the gelatin‐based hydrogel (GBH) wound dressing combined with adipose‐derived stem cells (ADSCs) were investigated using the mouse and porcine models. The analytical results showed that the ADSCs harvested from the porcine significantly increased cell growth and promoted cell differentiation (adipogenesis and osteogenesis) in comparison to the ADSCs harvested...
Three‐dimensional bioprinting is an innovative technique in tissue engineering, to create layer‐by‐layer structures, required for mimicking body tissues. However, synthetic bioinks do not generally possess high printability and biocompatibility at the same time. So, there is an urgent need for naturally derived bioinks that can exhibit such optimized properties. We used furfuryl‐gelatin as a novel,...
The spontaneous uptake of Ca2+‐ions is a unique property of alginate hydrogels, which, along with their high biocompatibility, disintegration (approximately within 2 weeks), and morphological similarity to heart tissue, makes them attractive as scaffolding materials in therapies in infarct myocardium. To shed light on the aforementioned ability, thorough theoretical calculations were carried out with...
Artificial tissue‐engineered grafts offer a potential alternative to autologous tissue grafts for patients, which can be traumatic. After decellularizing Papio hamadryas esophagus and studying the morphology and physical properties of the extracellular matrix (ECM), we generated electrospun polyamide‐6 based scaffolds to mimic it. The scaffolds supported a greater mechanical load than the native ECM...
Bone morphogenetic protein‐2 (BMP‐2) is commonly used to enhance bone regeneration. The potential of BMP‐2 for bone regeneration varies according to the concentration and release kinetics on the implanted site. Therefore, it is important to determine appropriate carriers of BMP‐2. However, no optimal delivery vehicles have been identified. In the present study, we used alginate microbeads as a delivery...
Novel neural interfaces capable of reliably capturing electrical signals are crucial for the development of prostheses. Longitudinal intrafascicular electrodes (LIFEs) have been proposed as a promising technology, and their feasibility and biocompatibility need to be investigated for long‐term implantation. In this study, custom‐designed 95%Pt–5%Ir intrafascicular electrodes were implanted into the...
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