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No current clinical treatments provide an ideal long‐term solution for repair of long bone segment defects. Incomplete healing prevents patients from returning to preinjury activity and ultimately requires additional surgery to induce healing. Obtaining autologous graft material is costly, incurs morbidity, requires surgical time, and quality material is finite. In this pilot study, 3D printed biomimetic...
CaSO4/CaPO4‐TCP bone graft substitute has been shown to be effective for treatment of bone lesion defects, but its mechanical, histological, and radiographic characteristics have not been studied in direct comparison with a conventional treatment such as cancellous allograft bone. Thirteen canines had a critical‐size axial defect created bilaterally into the proximal humerus. CaSO4/CaPO4‐TCP bone...
Biomaterials are used in the granular form to fill small bone defects. Granules can be prepared with a grinder from trabecular bone samples or provided as synthetic biomaterials by industry. Granules occupy the 3D‐space and create a macroporosity allowing invasion of vascular and bone cells when the inter‐granular pores are larger than 300 µm. We compared the 3D‐porosity of granule stacks obtained...
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