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Recent studies showed that mesenchymal stem cell (MSC) transplantation significantly alleviated tissue fibrosis; however, little is known about the efficacy on attenuating cutaneous scar formation. In this study, we established a dermal fibrosis model induced by bleomycin and evaluated the benefit of bone marrow‐derived mesenchymal stem cells (BM‐MSCs) on skin fibrosis development. Tracing assay of...
To investigate whether diabetes mellitus affects the wound‐healing‐promoting potential of adipose tissue‐derived stem cells, we designed a wound‐healing model using diabetic mice. We compared the degree of wound healing between wounds treated with normal adipose tissue‐derived stem cells and wounds treated with diabetic adipose tissue‐derived stem cells. We evaluated the wound‐healing rate, the epithelial...
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